Clarification of Acting CEO Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) CLARIFICATION OF ACTING CEO Shareholders are referred to the announcement published on SENS on 20 December 2021 entitled “Results of Annual General Meeting and Changes to Composition of Board and Board Committees” (“the Announcement”). In the Announcement, it was stated that Andrew Marshall was appointed as acting chief executive officer (“CEO”) and shall remain an employee of the Company in this role. For clarification, the board of directors of Ascendis Health (“the Board”) has approached Andrew about the acting CEO role while it continues its search for a permanent candidate. Andrew and the Board are still engaged in discussions in this regard and is subject to finalisation. 21 December 2021 Bryanston Sponsor Questco Corporate Advisory Proprietary Limited Date: 21-12-2021 02:38:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.