Dealings in securities by an associate of a director Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) DEALINGS IN SECURITIES BY AN ASSOCIATE OF A DIRECTOR In terms of paragraphs 3.63 to 3.74 of the Listings Requirements of the JSE Limited, the following information, relating to dealings in securities by an associate of a director, is disclosed: Name of Director: Carl Neethling Designation: Non-Executive Director Name and relationship of associate: Dendrobium Capital Proprietary Limited (“Dendrobium”). Carl Neethling is a director of Dendrobium Nature of transaction: On-market purchase Class of securities: Ordinary shares Extent of interest: Indirect beneficial Clearance to deal: Clearance to deal was not obtained Date of transaction: 12 May 2022 Highest price per share: R0.78 Lowest price per share: R0.65 Volume weighted average price per R0.69885 share: Number of securities: 260 000 Total value of securities: R181 700 RESPONSIBILITY STATEMENT The board of directors of Ascendis (the “Board”) accepts responsibility for the information contained in this announcement as it pertains to Ascendis. To the best of the Board's knowledge and belief, the information contained in this announcement as it pertains to Ascendis is true and nothing has been omitted which is likely to affect the importance of such information. Bryanston 20 May 2022 Sponsor Questco Corporate Advisory Proprietary Limited Date: 20-05-2022 02:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.